Further Studies on the Roles of Sodium and Potassium in the Generation of the Electro-Olfactogram Effects of mono-, di-, and trivalent cations

The ionic mechanisms underlying the generation of the electro-negative and positive "electro-olfactograms" (EOG's) have been studied in previous papers (Takagi and Wyse, 1965; Takagi, Wyse, and Yajima, 1966; Takagi, 1968; Takagi, Wyse, Ki tamura, and Ito, 1968). Briefly, the results showed that the negative EOG's primarily depend upon the entry of Na+ and the simultaneous exit of K +, and that neither Li +, tetraethyl ammonium (TEA+), choline +, hydrazine, nor sucrose can substitute for Na+; the positive EOG's primarily depend upon the entry of CIand the simultaneous exit of K +, and three anions, Br-, F, and H C O ~ can substitute for C1-.